Fabric-Based Electrochemical Glucose Sensor with Integrated Millifluidic Path from a Hydrophobic Batik Wax

Isa Anshori; Elfrida Vanesa Heriawan; Putri Yulianti Suhayat; Dedy H B Wicaksono; Samuel Priyantoro Kusumocahyo; Ardianto Satriawan; Wervyan Shalannanda; Latifa Dwiyanti; Casi Setianingsih; Murni Handayani

doi:10.3390/s23135833

Fabric-Based Electrochemical Glucose Sensor with Integrated Millifluidic Path from a Hydrophobic Batik Wax

Sensors (Basel). 2023 Jun 22;23(13):5833. doi: 10.3390/s23135833.

Affiliations

¹ School of Electrical Engineering and Informatics, Bandung Institute of Technology, Bandung 40132, Indonesia.
² Research Center for Nanosciences and Nanotechnology (RCNN), Bandung Institute of Technology, Bandung 40132, Indonesia.
³ Department of Biomedical Engineering, Faculty of Life Sciences and Technology, Swiss German University, Tangerang 15143, Indonesia.
⁴ Department of Chemical Engineering, Faculty of Life Sciences and Technology, Swiss German University, Tangerang 15143, Indonesia.
⁵ Department of Computer Engineering, School of Electrical Engineering, Telkom University, Bandung 40257, Indonesia.
⁶ Research Center for Advanced Materials-National Research and Innovation Agency (BRIN), Tangerang Selatan 15314, Indonesia.

Abstract

In recent years, measuring and monitoring analyte concentrations continuously, frequently, and periodically has been a vital necessity for certain individuals. We developed a cotton-based millifluidic fabric-based electrochemical device (mFED) to monitor glucose continuously and evaluate the effects of mechanical deformation on the device's electrochemical performance. The mFED was fabricated using stencil printing (thick film method) for patterning the electrodes and wax-patterning to make the reaction zone. The analytical performance of the device was carried out using the chronoamperometry method at a detection potential of -0.2 V. The mFED has a linear working range of 0-20 mM of glucose, with LOD and LOQ of 0.98 mM and 3.26 mM. The 3D mFED shows the potential to be integrated as a wearable sensor that can continuously measure glucose under mechanical deformation.

Keywords: chemical and biological sensor; continuous glucose monitoring; fabric-based; millifluidic devices and lab-on-chip devices; sensor testing and evaluation; stencil printing.

MeSH terms

Biosensing Techniques*
Electrochemical Techniques / methods
Electrodes
Glucose*
Humans
Hydrophobic and Hydrophilic Interactions
Printing
Textiles

Substances

Glucose

Grants and funding

The authors thank the financial support from the 2023 Research Grant MUDA—HEBAT of the School of Electrical Engineering and Informatics, Bandung Institute of Technology with the grant number 984/IT1.C12/SK-KU/2023. The authors also thank the research support from Telkom University and Swiss German University.