Cysteine redox chemistry is widely used in nature to direct protein assembly, and in recent years it has inspired chemists to design self-assembling peptides too. In this concise review, we describe the progress in the field focusing on the recent advancements that make use of Cys thiol-disulfide redox chemistry to modulate hydrogelation of various peptide classes.
Keywords: amyloid; cysteine; disulfide; fibrils; hydrogels; peptide; redox; self-assembly; supramolecular; thiol.