Synchronous multiple primary malignancies of clear cell renal cell carcinoma with sarcomatoid, thyroid carcinoma: a case report

Front Oncol. 2023 Jun 27:13:1174306. doi: 10.3389/fonc.2023.1174306. eCollection 2023.

Abstract

Multiple primary malignant neoplasms (MPMNs) are defined as the presence of two or more malignancies with different histologies in the same patient. MPMNs are rare, accounting for fewer than 4% of all tumor cases. Depending on the time interval between the diagnosis of the different malignancies, they are classified as either simultaneous or metachronous MPMNs, with simultaneous being rarer in MPMNs. Here, we present a 63-year-old female patient presenting with multiple primary renal and thyroid carcinomas and discuss the risk factors, treatment options, and prognosis of rare dual carcinomas. We focus on managing multidisciplinary teams and selecting individualized treatment options to deliver valuable treatment strategies to patients.

Keywords: case report; clear cell renal cell carcinoma with sarcomatoid; multidisciplinary; multiple primary malignancies; papillary thyroid carcinoma.

Publication types

  • Case Reports

Grants and funding

Funding from Medical Scientific Research Foundation of Guangdong Province, China (Grant No. B2021114) is gratefully acknowledged.