Novel PAX3::INO80D Fusion in Biphenotypic Sinonasal Sarcoma in an Adult

JAMA Otolaryngol Head Neck Surg. 2023 Sep 1;149(9):849-850. doi: 10.1001/jamaoto.2023.1708.

Authors

Ariel Viramontes¹, Nicole Mueller¹, Christopher D Gocke², Timothy R Deklotz³, Metin Ozdemirli¹

Affiliations

¹ Department of Pathology and Laboratory Medicine, MedStar Georgetown University Hospital, Washington, DC.
² Department of Pathology, Oncology and Genetic Medicine, Johns Hopkins University Hospital, Baltimore, Maryland.
³ Department of Otolaryngology, MedStar Georgetown University Hospital, Washington, DC.

PMID: 37440250
DOI: 10.1001/jamaoto.2023.1708

No abstract available

Plain language summary

This case report describes a novel gene fusion of PAX3::INO80D in a biphenotypic sinonasal carcinoma in a woman in her 40s.

MeSH terms

Adult
Humans
PAX3 Transcription Factor
Paranasal Sinus Neoplasms* / diagnostic imaging
Paranasal Sinus Neoplasms* / genetics
Sarcoma* / genetics
Transcription Factors

Substances

Transcription Factors
PAX3 protein, human
PAX3 Transcription Factor