Longitudinal Molecular Analysis of Tumor Exome and Transcriptome to Evaluate Clonal Evolution and Identify Novel Therapeutic Targets in Thymoma

JCO Precis Oncol. 2023 Jul:7:e2300107. doi: 10.1200/PO.23.00107.

Authors

Christopher S Nabel^{1

2

3}, Yin P Hung^{2

4}, Anna Kurilovich⁵, Aleksandra Lopareva⁵, Dora Dias-Santagata^{2

4}, Nikita Batashkov⁵, Dmitry Tabakov⁵, Maria Sorokina⁵, Aleksey Makarov⁵, Georgy Sagaradze⁵, Anna Butusova⁵, Olga Kudryashova⁵, Lev Bedniagin⁵, Cameron D Wright^{2

6}, Nara Shin⁵, Alexander Bagaev⁵, Ekaterina Postovalova⁵, Abner Louissaint Jr^{2

4}

Affiliations

¹ Department of Medicine, Massachusetts General Hospital, Boston, MA.
² Harvard Medical School, Boston, MA.
³ Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA.
⁴ Department of Pathology, Massachusetts General Hospital, Boston, MA.
⁵ BostonGene, Waltham, MA.
⁶ Department of Surgery, Massachusetts General Hospital, Boston, MA.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Clonal Evolution
Exome / genetics
Humans
Thymoma* / genetics
Thymus Neoplasms* / diagnosis
Thymus Neoplasms* / drug therapy
Thymus Neoplasms* / genetics
Transcriptome / genetics