Efficacy of an Educational Intervention for Sodium Restriction in Patients with Hypertension: A Randomized Controlled Trial

Nutrients. 2023 Apr 30;15(9):2159. doi: 10.3390/nu15092159.

Abstract

There is sound evidence showing the efficacy of non-pharmacological interventions in lowering blood pressure (BP); however, adherence is usually poor. Interventions to induce behavioral changes aim to improve the ability to read labels, choose foods, and eat low-sodium meals, reinforcing adherence to sodium restriction. In this randomized parallel-controlled trial, we assessed the effectiveness of an educational intervention using the Dietary Sodium Restriction Questionnaire (DSRQ) scores. A follow-up period of 6 months was conducted. Participants were randomized into (1) an educational intervention provided by a registered dietitian on individual visits and dietary planning; (2) a control group with the usual care and dietary recommendations. Patients underwent 24-h ambulatory BP monitoring, 12-h fasting blood tests, spot urine collection, and assessment using DSRQ. We randomized 120 participants (67.5% women and 68.3% Caucasians), and 25 participants were lost to follow-up. The 24-h sodium urinary excretion changed in the control (Δ -1610 mg/day; 95% confidence interval [CI] -1800 to -1410) and intervention groups (Δ -1670 mg/day; 95% CI -1800 to -1450) over time. There was no significant difference in the 24-h estimated sodium between groups. In hypertensive patients, DSRQ-based educational intervention is effective for improving the ability to detect and overcome obstacles to a low-sodium restriction diet but is as effective as dietary recommendations for lowering sodium.

Keywords: Dietary Sodium Restriction Questionnaire; adherence; dietary sodium restriction; educational intervention; hypertension; low-sodium diet; sodium restriction.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Diet, Sodium-Restricted
  • Female
  • Humans
  • Hypertension* / therapy
  • Male
  • Meals
  • Sodium
  • Sodium Chloride, Dietary
  • Sodium, Dietary*

Substances

  • Sodium
  • Sodium, Dietary
  • Sodium-24
  • Sodium Chloride, Dietary