Does postcholecystectomy increase the risk of colorectal cancer?

Zhenyu Dong; Ruixian Shi; Pengda Li; Xiaobiao Song; Fan Dong; Jianmin Zhu; Riga Wu; Zhi Liang; Mingyue Du; Jijun Wang; Zhigang Yang

doi:10.3389/fmicb.2023.1194419

Does postcholecystectomy increase the risk of colorectal cancer?

Front Microbiol. 2023 Jun 22:14:1194419. doi: 10.3389/fmicb.2023.1194419. eCollection 2023.

Authors

Zhenyu Dong^#^{1

2}, Ruixian Shi^#^{3

4}, Pengda Li^#^{1

2}, Xiaobiao Song¹, Fan Dong¹, Jianmin Zhu¹, Riga Wu⁵, Zhi Liang², Mingyue Du², Jijun Wang¹, Zhigang Yang⁶

Affiliations

¹ Department of General Surgery, Baotou Central Hospital, Baotou, Inner Mongolia, China.
² Baotou Medical College, Baotou, Inner Mongolia, China.
³ Department of Neurology, Baotou Central Hospital, Baotou, Inner Mongolia, China.
⁴ Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
⁵ Department of General Surgery, The Second Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia, China.
⁶ Department of Urology, Baotou Central Hospital, Baotou, Inner Mongolia, China.

^# Contributed equally.

Abstract

With the increasing number of cholecystectomy and the high proportion of colorectal cancer in malignant tumors, the question of whether cholecystectomy is a risk factor for colorectal disease has been widely concerned. After reviewing the literature at home and abroad, the authors will summarize the research progress of the correlation between the occurrence of colorectal tumors after cholecystectomy, in order to provide help for the prevention and treatment of colorectal tumors.

Keywords: bile acid; cholecystectomy; colorectal cancer; intestinal flora; microbiome.

Publication types

Review