Custom-made meniscus biofabrication

Hélène Vignes; Rana Smaida; Guillaume Conzatti; Guoqiang Hua; Nadia Benkirane-Jessel

doi:10.1016/j.tibtech.2023.06.003

Custom-made meniscus biofabrication

Trends Biotechnol. 2023 Dec;41(12):1467-1470. doi: 10.1016/j.tibtech.2023.06.003. Epub 2023 Jul 7.

Authors

Hélène Vignes¹, Rana Smaida¹, Guillaume Conzatti¹, Guoqiang Hua¹, Nadia Benkirane-Jessel²

Affiliations

¹ French National Institute of Health and Medical Research (INSERM), UMR 1260, Regenerative Nanomedicine (RNM), 1 Rue Eugène Boeckel, 67000 Strasbourg, France; Université de Strasbourg (Faculté de Médecine, Faculté de Chirurgie Dentaire, Faculté de Pharmacie), Strasbourg, France.
² French National Institute of Health and Medical Research (INSERM), UMR 1260, Regenerative Nanomedicine (RNM), 1 Rue Eugène Boeckel, 67000 Strasbourg, France; Université de Strasbourg (Faculté de Médecine, Faculté de Chirurgie Dentaire, Faculté de Pharmacie), Strasbourg, France. Electronic address: nadia.jessel@inserm.fr.

PMID: 37423883
DOI: 10.1016/j.tibtech.2023.06.003

Abstract

Reconstructing the meniscus is not currently possible due to its intricate and heterogeneous structure. In this forum, we first discuss the shortcomings of current clinical strategies in meniscus repair. Then, we describe a new promising cell-based, ink-free 3D biofabrication technology to produce tailor-made large-scale functional menisci.

Keywords: biofabrication; meniscus repair; regenerative medicine; stem cells; tissue engineering.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bioprinting*
Meniscus*
Tissue Engineering
Tissue Scaffolds / chemistry