Exploring the Applications of Indocyanine Green in Robot-Assisted Urological Surgery: A Comprehensive Review of Fluorescence-Guided Techniques

Sensors (Basel). 2023 Jun 11;23(12):5497. doi: 10.3390/s23125497.

Abstract

This comprehensive review aims to explore the applications of indocyanine green (ICG) in robot-assisted urological surgery through a detailed examination of fluorescence-guided techniques. An extensive literature search was conducted in PubMed/MEDLINE, EMBASE and Scopus, using keywords such as "indocyanine green," "ICG", "NIRF", "Near Infrared Fluorescence", "robot-assisted", and "urology". Additional suitable articles were collected by manually cross-referencing the bibliography of previously selected papers. The integration of the Firefly® technology in the Da Vinci® robotic system has opened new avenues for the advancement and exploration of different urological procedures. ICG is a fluorophore widely used in near-infrared fluorescence-guided techniques. The synergistic combination of intraoperative support, safety profiles and widespread availability comprises an additional asset that empowers ICG-guided robotic surgery. This overview of the current state of the art illustrates the potential advantages and broad applications of combining ICG-fluorescence guidance with robotic-assisted urological surgery.

Keywords: ICG; NIRF; firefly; fluorescence imaging; indocyanine green; near-infrared fluorescence; robotic surgery; urology.

Publication types

  • Review

MeSH terms

  • Fluorescence
  • Fluorescent Dyes
  • Indocyanine Green
  • Robotic Surgical Procedures* / methods
  • Robotics*

Substances

  • Indocyanine Green
  • Fluorescent Dyes

Grants and funding

This research received no external funding.