The role of cannabidiol in aging

Biomed Pharmacother. 2023 Sep:165:115074. doi: 10.1016/j.biopha.2023.115074. Epub 2023 Jul 6.

Abstract

Aging is usually considered a key risk factor associated with multiple diseases, such as neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden of age-related diseases has become a global challenge. It is of great significance to search for drugs to extend lifespan and healthspan. Cannabidiol (CBD), a natural nontoxic phytocannabinoid, has been regarded as a potential candidate drug for antiaging. An increasing number of studies have suggested that CBD could benefit healthy longevity. Herein, we summarized the effect of CBD on aging and analyzed the possible mechanism. All these conclusions may provide a perspective for further study of CBD on aging.

Keywords: Age-related diseases; Aging; Cannabidiol; Lifespan; Strategies.

Publication types

  • Review

MeSH terms

  • Cannabidiol* / pharmacology
  • Cannabidiol* / therapeutic use
  • Humans
  • Longevity
  • Neurodegenerative Diseases*

Substances

  • Cannabidiol