The efficacy of Fuke Qianjin tablets combined with clomiphene citrate on infertility patients with polycystic ovary syndrome: A retrospective analysis

Medicine (Baltimore). 2023 Jul 7;102(27):e34162. doi: 10.1097/MD.0000000000034162.

Abstract

Purpose: Clinical efficacy of Fuke Qianjin tablets combined with clomiphene citrate on infertility patients with polycystic ovary syndrome (PCOS) was expected to be retrospectively analyzed in this study.

Methods: In this paper, 100 infertility patients with PCOS were selected and divided into the observation and control groups based on different medications. Firstly, clinical data of both groups of patients were acquired. Then, the uterine receptivity and ovarian status, the levels of sex hormones, inflammation and oxidative stress, and the pregnancy outcomes between the 2 groups were compared and analyzed before and after treatment.

Results: After a variety of comparisons and analyses, Fuke Qianjin tablets combined with clomiphene citrate were confirmed to improve the uterine receptivity and ovarian status, levels of sex hormone, inflammation and oxidative stress, and pregnancy outcomes in infertility patients with PCOS.

Conclusions: Overall, Fuke Qianjin tablets + clomiphene citrate treatment shows good clinical efficacy and is worth promotion in clinical practice.

MeSH terms

  • Clomiphene / therapeutic use
  • Female
  • Fertility Agents, Female / therapeutic use
  • Humans
  • Infertility, Female* / drug therapy
  • Infertility, Female* / etiology
  • Inflammation / drug therapy
  • Ovulation Induction
  • Polycystic Ovary Syndrome* / complications
  • Polycystic Ovary Syndrome* / drug therapy
  • Pregnancy
  • Retrospective Studies
  • Tablets

Substances

  • Clomiphene
  • Tablets
  • Fertility Agents, Female