Eclampsia: A Critical Pregnancy Complication Demanding Enhanced Maternal Care: A Review

Med Sci Monit. 2023 Jul 7:29:e939919. doi: 10.12659/MSM.939919.

Abstract

Eclampsia is the most serious pregnancy complication and one of the main causes of death of pregnant and delivering women. The mortality rate of young mothers is 5-20%, emphasizing the severity of this pregnancy-related disorder. Today many centers have only rare opportunities to see and deal with eclampsia cases; therefore, it is very important to bring this emergency medical condition to the attention of attending physicians. All patients with eclampsia, and after eclamptic seizures, should be treated in an intensive care unit. However, taking into account clinical realities, especially in developing countries, this is not always possible. It is necessary for all gynecologists-obstetricians to be fully prepared for eclampsia, although its occurrence is very rare. Drug treatment aims to stop eclampsia seizures and prevent reoccurrence of convulsions and complications. Magnesium sulphate is the drug of first choice used in treatment of eclampsia seizure, whereas treatment with the use of antihypertensive drugs and proper blood pressure control is one of the most important factors effectively reducing the risk of deaths or acute complications and poor pregnancy outcomes. The most urgent part of the treatment is the lifesaving procedure involving airways patency assessment, maintenance of breathing and blood circulation of the mother, securing an adequate oxygen level of the mother and thereby of the fetus, and prevention of injuries. This review aims to present an overview of the current prevalence, diagnosis, and management of eclampsia and the need for improved maternal care.

Publication types

  • Review

MeSH terms

  • Eclampsia* / drug therapy
  • Female
  • Humans
  • Magnesium Sulfate / therapeutic use
  • Pre-Eclampsia* / diagnosis
  • Pre-Eclampsia* / therapy
  • Pregnancy
  • Pregnancy Complications* / drug therapy
  • Pregnancy Outcome
  • Seizures / drug therapy

Substances

  • Magnesium Sulfate