Squamous Cell Carcinoma of perineal area developed from the Buschke-Löwenstein tumor

Folia Med Cracov. 2023 Apr 30;63(1):91-96. doi: 10.24425/fmc.2023.145432.

Abstract

The Buschke-Löwenstein tumor is a rare disease associated with human papillomavirus infection. The condition manifests with an ulcerative, exophytic tumor localized in the perineal area. Generally considered as non-cancerous, the growth may develop malignant transformation. Our manuscript highlights the importance of early diagnosis with histopathological analysis.

Keywords: Buschke–Löwenstein tumor; HPV vaccination; giant condyloma acuminatum; human papillomavirus; malignant transformation.

MeSH terms

  • Buschke-Lowenstein Tumor* / pathology
  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / surgery
  • Condylomata Acuminata* / pathology
  • Humans
  • Perineum / pathology