Stereotactic ablation: A game changer?

J Med Imaging Radiat Oncol. 2023 Dec;67(8):886-894. doi: 10.1111/1754-9485.13555. Epub 2023 Jul 3.

Abstract

For both primary and metastatic liver cancer, thermal ablation represents an interesting alternative to surgery. However, except for a small fraction of patients, conventional ultrasound- and CT-guided single-probe approaches have not achieved oncologic outcomes comparable with surgery. In this overview, we describe our stereotactic ablation workflow and discuss the short- and long-term results of stereotactic radiofrequency ablation (SRFA) and stereotactic microwave ablation (SMWA) for the treatment of primary and secondary liver tumours. The advantages of this method are discussed together with a summary of the existing stereotactic techniques for thermal ablation and the clinical data that support them. Stereotactic ablation is based on an optical navigation system and a specialized aiming tool. The workflow includes advanced three-dimensional planning, precise needle/probe placements according to the plan and intraoperative image fusion to check the needle positions and the ablation margins. Stereotactic ablation offers all the advantages of a minimally invasive procedure while producing oncological results comparable with surgery. The number of locally treatable liver cancers may be significantly expanded with these cutting-edge instruments and methods. We firmly believe that it can become a cornerstone in the treatment of liver cancers.

Keywords: image fusion; liver tumour; microwave ablation; radiofrequency ablation; stereotaxy.

MeSH terms

  • Catheter Ablation* / methods
  • Humans
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / surgery
  • Neoplasms, Second Primary* / surgery
  • Radiofrequency Ablation*
  • Surgery, Computer-Assisted* / methods