Risk factors for depression in patients with chronic obstructive pulmonary disease

Respir Physiol Neurobiol. 2023 Sep:315:104110. doi: 10.1016/j.resp.2023.104110. Epub 2023 Jul 1.

Abstract

Depression, anxiety, and panic disorders are common in chronic obstructive pulmonary disease (COPD) and important for the further course of the disease, as they are associated with increased hospital admissions, longer hospital stays, more frequent doctor visits, and a worsened quality of life. There are also indications of premature death in affected patients. Therefore, knowledge of the risk factors for depression in COPD patients is all the more important for early detection and treatment. Hence, Embase, the Cochrane Library, and the MEDLINE/PubMed databases were analyzed for studies on these risk factors. The main factors are as follows: female gender; older/younger age; living alone; higher education; unemployment; retirement; a low quality of life; social isolation; high/low income; high cigarette and alcohol consumption; poor physical fitness; severe respiratory symptoms; high/low body mass index, airway obstruction, dyspnea, exercise capacity index scores; and comorbidities (mainly heart disease, cancer, diabetes, and stroke). This article presents the analyzed medical literature.

Keywords: Anxiety; COPD; Causes; Comorbidities; Depression; Risk factors.

Publication types

  • Review

MeSH terms

  • Comorbidity
  • Depression* / epidemiology
  • Depression* / etiology
  • Dyspnea
  • Female
  • Humans
  • Pulmonary Disease, Chronic Obstructive* / complications
  • Pulmonary Disease, Chronic Obstructive* / epidemiology
  • Pulmonary Disease, Chronic Obstructive* / therapy
  • Quality of Life
  • Risk Factors