The association between callous-unemotional traits and substance use in childhood and adolescence: A systematic review and meta-analysis

J Affect Disord. 2023 Oct 1:338:502-517. doi: 10.1016/j.jad.2023.06.051. Epub 2023 Jun 29.

Abstract

Callous-unemotional (CU) traits are characterized by a lack of guilt and empathy, restricted affect, and low concern about performance, and are increasingly recognized as co-occurring with substance use in youth. However, there is mixed evidence concerning whether they make a unique contribution to substance use. This systematic review and meta-analysis sought to quantify the association between CU traits and substance use in childhood, accounting for potential moderators including sample characteristics (age, gender, community versus clinical/forensic samples), CU traits measure and informant, and study design (cross-sectional or longitudinal). Separate meta-analyses were conducted for alcohol, cannabis, and a substance use composite. Small, significant associations were found between CU traits and alcohol (θ = 0.17), cannabis (θ = 0.17) and the substance use composite (θ = 0.15), which were present in both community and clinical/forensic samples. Findings suggest that CU traits co-occur with a range of substance use problems, and that CU traits should be considered in assessments of youth presenting with substance use problems regardless of the nature of the setting.

Keywords: Alcohol; Callous-unemotional; Childhood; Drugs; Substance use; cannabis.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Adolescent
  • Conduct Disorder* / epidemiology
  • Conduct Disorder* / psychology
  • Cross-Sectional Studies
  • Emotions
  • Empathy
  • Guilt
  • Humans
  • Substance-Related Disorders* / epidemiology
  • Substance-Related Disorders* / psychology