Autism trends in a medium size coastal town of England

PLoS One. 2023 Jun 30;18(6):e0287808. doi: 10.1371/journal.pone.0287808. eCollection 2023.

Abstract

Autism spectrum disorder (ASD) is a complex set of neurodevelopmental conditions which affects just under 1% of the global population. This study aims to investigate the trends in ASD diagnoses in a typical English deprived coastal community over the last two decades. ASD information for patients registered at Fleetwood GP practices were provided for the period between July 1952 to March 2022. The incidence and prevalence were calculated and Poisson regression modelling was employed to estimate the effects of age and sex on the number of ASD diagnoses over time. The study shows that there has been an upward trend in the number of ASD diagnoses over the past two decades. Model's results showed that sex differences in ASD diagnoses are less pronounced when accounting for time trends. The study findings show that Fleetwood has experienced a similar rise in ASD cases as the rest of the UK, most likely due to increased awareness that may explain the time effects over gender differences. However, due to the small sample size of the study, confirmation of the gender results and identification of the factors determining the temporal trends are needed in order to determine the gender effects in ASD diagnosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autism Spectrum Disorder* / epidemiology
  • Autistic Disorder* / epidemiology
  • England / epidemiology
  • Female
  • Humans
  • Male
  • Neurodevelopmental Disorders*
  • Records

Grants and funding

This work was funded by the NHS, Wyre Council, Healthier Fleetwood, and Lancaster University ESPRC Impact Accelerator Account (reference: IAA: The use of innovative statistical methods aimed at improving the communities afflicted by COVID-19 patients). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.