Synchronous Treatment of Breast Cancer Hepatic Metastases by Transarterial Radioembolization and Radiofrequency Thermoablation: A Case Report

Clin Nucl Med. 2023 Sep 1;48(9):e446-e448. doi: 10.1097/RLU.0000000000004766. Epub 2023 Jun 29.

Abstract

In a 51-year-old woman affected by breast cancer, hepatic recurrence of disease was managed by concurrent 90 Y-labeled glass microsphere embolization (transarterial radioembolization) and radiofrequency thermoablation. Intention-to-treat target, candidate to radioembolization, was in the IV hepatic segment; another lesion, managed with radiofrequency thermoablation, was in the VI-VII hepatic segment. Concomitant correction of a duodenocephalopancreatic shunting was performed as well. Thermoablation did not interfere with distribution of 99m Tc-macroaggregated albumin and 90 Y-labeled microspheres to the target and healthy liver. At our knowledge, this is the first report that combines 2 locoregional procedures in different hepatic segments on the same day.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms* / therapy
  • Embolization, Therapeutic*
  • Female
  • Humans
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / secondary
  • Liver Neoplasms* / therapy
  • Microspheres
  • Middle Aged
  • Retrospective Studies
  • Technetium Tc 99m Aggregated Albumin
  • Yttrium Radioisotopes / therapeutic use

Substances

  • Technetium Tc 99m Aggregated Albumin
  • Yttrium Radioisotopes