Effects of Oat Bran Addition on the Growth Performance and Intestinal Health of Nile Tilapia (Oreochromis niloticus) Exposed to Copper Ions

Chunze Guo; Yingchao Zhang; Xuekai Wang; Kuikui Ni; Qiang Hao; Zhen Zhang; Zhigang Zhou; Fuyu Yang

doi:10.1155/2023/5329546

Effects of Oat Bran Addition on the Growth Performance and Intestinal Health of Nile Tilapia (Oreochromis niloticus) Exposed to Copper Ions

Aquac Nutr. 2023 Jun 20:2023:5329546. doi: 10.1155/2023/5329546. eCollection 2023.

Authors

Chunze Guo¹, Yingchao Zhang², Xuekai Wang¹, Kuikui Ni¹, Qiang Hao³, Zhen Zhang³, Zhigang Zhou³, Fuyu Yang¹

Affiliations

¹ College of Grassland Science and Technology, China Agricultural University, Beijing 100193, China.
² College of Life Science, North China University of Science and Technology, Tangshan 063210, China.
³ Key Laboratory for Feed Biotechnology of the Ministry of Agriculture and Rural Affairs, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Abstract

This study investigated the effects of the oat bran addition on the growth performance and intestinal health of Nile tilapia (Oreochromis niloticus) exposed to copper ions. Four groups of diets containing 0%, 5%, 10%, and 20% oat bran were fed to Nile tilapia for four weeks. The results showed that oat bran had a dose-dependent effect on the growth performance of Nile tilapia. The addition of oat bran can increase the relative abundance of Delftia, which is capable of degrading heavy metals in the intestinal tract and alleviating the intestinal damage caused by copper ion stress. Compared to the control group, the 5% oat bran group had an increased intestinal antioxidant capacity. The relative gene expression of proinflammatory factors (NF-κB, IL-1β) was significantly downregulated in the 5% oat bran group (P < 0.05), and the relative gene expression of anti-inflammatory factors (TGF-β), HIF-1α, occludin, and claudin was significantly upregulated (P < 0.05). In conclusion, we suggest that 5% oat bran should be added to the diet to improve the growth performance of Nile tilapia and alleviate the negative effects of copper ion stress on intestinal health.