Role of the SARS‑COV2 infection in the evolution of acute pancreatitis (Review)

Biomed Rep. 2023 Jun 12;19(1):49. doi: 10.3892/br.2023.1632. eCollection 2023 Jul.

Abstract

Acute pancreatitis is characterized as an inflammatory illness that is life-threatening and causes necrosis as well as simple edema when pancreatic enzymes are activated intraglandularly. It is not known whether severe acute respiratory syndrome coronavirus 2 causes acute pancreatitis. Patients with acute pancreatitis who test positive for coronavirus disease 2019 (COVID-19) frequently have biliary or alcoholic causes. It is unclear how common acute pancreatitis is in patients with COVID-19. By contrast with patients without COVID-19, however, COVID-19-positive patients with acute pancreatitis have a higher mortality as well as a higher risk of necrosis and admission to an intensive care unit. The most common cause of mortality in COVID-19-positive individuals with concurrent severe pancreatitis is acute respiratory distress syndrome. The present study discussed research on the link between COVID-19 infection and acute pancreatitis.

Keywords: acute pancreatitis; severe acute respiratory syndrome coronavirus 2 infection; vaccine.

Publication types

  • Review

Grants and funding

Funding: The present study was supported by S.C. TOP DIABET S.R.L., Craiova, Romania, Research Grant of the University of Medicine and Pharmacy of Craiova (grant no. 26/727/4/27.07.2022).