Correlation between the dopaminergic system and inflammation disease: a review

Mol Biol Rep. 2023 Aug;50(8):7043-7053. doi: 10.1007/s11033-023-08610-2. Epub 2023 Jun 29.

Abstract

The dopaminergic system is inextricably linked with neurological diseases and addiction. In recent years, many studies have found that the dopaminergic system involves in inflammatory diseases, particularly neuroinflammatory diseases development; This review summarizes the studies of dopaminergic system in inflammatory diseases, and specifically highlights the mechanisms of how dopaminergic system regulates inflammation; In addition, we speculate that there are some cavities in current research, including mixed usage of inhibitors, agonists and lack of systematic controls; We expect this review would provide directions to future research of dopaminergic system and inflammatory diseases.

Keywords: Dopamine.; Dopaminergic system; Inflammation disease.

Publication types

  • Review

MeSH terms

  • Dopamine*
  • Humans
  • Inflammation
  • Nervous System Diseases*

Substances

  • Dopamine