Secondary perichondrium patch to enhance cartilage graft during endoscopic cartilage myringoplasty

Eur Arch Otorhinolaryngol. 2023 Dec;280(12):5277-5283. doi: 10.1007/s00405-023-08039-0. Epub 2023 Jun 29.

Abstract

Objectives: The aim of this study was to explore the method of adding a secondary perichondrium patch to enhance the primary cartilage-perichondrium patch during endoscopic myringoplasty and to evaluate the effectiveness of this method in terms of healing rate and post-operative hearing of patients with poor prognostic factors (eustachian tube dysfunction, large perforations, subtotal perforations, and anterior marginal perforations).

Design: This retrospective study analyzed a total of 80 patients (36 females and 44 males, median age of 40.55 years) who had received a secondary perichondrium patch during endoscopic cartilage myringoplasty. Patients were followed up for 6 months. Healing rates, complications, preoperative and postoperative pure-tone average (PTA) and air-bone gap (ABG) were analyzed.

Results: At 6-month follow-up, the healing rate of tympanic membrane was 97.5% (78/80). The mean pure-tone average (PTA) improved from 43.18 ± 14.57 dB HL pre-operatively to 27.08 ± 9.36 dB HL 6 months after the operation (P = 0.002). Similarly, the mean ABG improved from 19.05 ± 5.72 dB HL pre-operatively to 9.36 ± 3.75 dB HL (P = 0.0019) at 6 months after the operation. Major complications were not observed during follow-up.

Conclusions: The use of a secondary perichondrium patch during endoscopic cartilage myringoplasty for large, subtotal and marginal tympanic membrane perforations achieved a high healing rate and a statistically significant hearing gain with low incidence of complications.

Keywords: Cartilage graft; Endoscopic myringoplasty; Secondary patch; Tympanic membrane perforation.

MeSH terms

  • Adult
  • Cartilage / transplantation
  • Female
  • Humans
  • Male
  • Myringoplasty* / methods
  • Retrospective Studies
  • Treatment Outcome
  • Tympanic Membrane
  • Tympanic Membrane Perforation* / surgery