JPH203, a LAT1 inhibitor, alleviates steroid-resistant murine airway inflammation mediated by Th17 cells

Allergy. 2023 Oct;78(10):2780-2783. doi: 10.1111/all.15798. Epub 2023 Jun 29.
No abstract available

Keywords: JPH203; L-type amino acid transporter 1 (LAT1); amino acid transporter; immunosuppressant; intractable asthma.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Benzoxazoles* / pharmacology
  • Humans
  • Inflammation / drug therapy
  • Mice
  • Steroids
  • Th17 Cells*

Substances

  • 2-amino-3-(4-((5-amino-2-phenylbenzo(d)oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid
  • Benzoxazoles
  • Steroids