Application of Flow Cytometry in the Diagnosis of Bovine Epidemic Disease

Viruses. 2023 Jun 15;15(6):1378. doi: 10.3390/v15061378.

Abstract

As science and technology continue to advance, the use of flow cytometry is becoming more widespread. It can provide important information about cells in the body by detecting and analysing them, thereby providing a reliable basis for disease diagnosis. In the diagnosis of bovine epidemic diseases, flow cytometry can be used to detect bovine viral diarrhoea, bovine leukaemia, bovine brucellosis, bovine tuberculosis, and other diseases. This paper describes the structure of a flow cytometer (liquid flow system, optical detection system, data storage and analysis system) and its working principles for rapid quantitative analysis and sorting of single cells or biological particles. Additionally, the research progress of flow cytometry in the diagnosis of bovine epidemic diseases was reviewed in order to provide a reference for future research and application of flow cytometry in the diagnosis of bovine epidemic diseases.

Keywords: bovine epidemic diseases; diagnose; flow cytometry.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases* / diagnosis
  • Epidemics / veterinary
  • Flow Cytometry* / veterinary

Grants and funding

The Inner Mongolia Natural Science Foundation (2021LHMS03008), the multi-disciplinary cross research project of basic scientific research business fees of universities directly under Inner Mongolia (GXKY22003).