PRRSV Elimination in a Farrow-to-Finish Pig Herd Using Herd Closure and Rollover Approach

Ruiming Hu; Tiansheng Zhang; Rongbin Lai; Zhen Ding; Yu Zhuang; Hao Liu; Huabin Cao; Xiaona Gao; Junrong Luo; Zheng Chen; Caiying Zhang; Ping Liu; Xiaoquan Guo; Guoliang Hu; Nengshui Ding; Shunzhou Deng

doi:10.3390/v15061239

PRRSV Elimination in a Farrow-to-Finish Pig Herd Using Herd Closure and Rollover Approach

Viruses. 2023 May 25;15(6):1239. doi: 10.3390/v15061239.

Authors

Ruiming Hu^{1

2}, Tiansheng Zhang³, Rongbin Lai³, Zhen Ding^{1

2}, Yu Zhuang^{1

2}, Hao Liu¹, Huabin Cao^{1

2}, Xiaona Gao^{1

2}, Junrong Luo^{1

2}, Zheng Chen^{1

2}, Caiying Zhang^{1

2}, Ping Liu^{1

2}, Xiaoquan Guo^{1

2}, Guoliang Hu^{1

2}, Nengshui Ding^{1

3

4}, Shunzhou Deng^{1

2}

Affiliations

¹ Department of Veterinary Medicine, College of Animal Science and Technology, Jiangxi Agricultural University, No. 1101 Zhimin Avenue, Nanchang 330045, China.
² Jiangxi Provincial Key Laboratory for Animal Disease Diagnosis and Control, Institute of Animal Population Health, Jiangxi Agricultural University, Nanchang 330045, China.
³ Key Laboratory of Swine Nutrition and Feed Science of Fujian Province, Aonong Group, Zhangzhou 363000, China.
⁴ State Key Laboratory for Pig Genetic Improvement and Production Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Abstract

It is well established that PRRSV elimination is an effective strategy for PRRS control, but published reports concerning successful PRRSV elimination cases in farrow-to-finishing herds are rare. Here, we have reported a successful PRRSV elimination case in a farrow-to-finish herd by employing a "herd closure and rollover" approach with some modifications. Briefly, the introduction of pigs to the herd was stopped and normal production processes were maintained until the herd reached a PRRSV provisional negative status. During the herd closure, strict biosecurity protocols were implemented to prevent transmission between nursery pigs and sows. In the current case, introducing gilts before herd closure and live PRRSV exposure were skipped. In the 23rd week post-outbreak, the pre-weaning piglets started to show 100% PRRSV negativity in qPCR tests. In the 27th week, nursery and fattening barns fully launched depopulation. In the 28th week, nursery and fattening houses reopened and sentinel gilts were introduced into gestation barns. Sixty days post-sentinel gilt introduction, the sentinel pigs maintained being PRRSV antibody negative, manifesting that the herd matched the standard of the provisional negative status. The production performance of the herd took 5 months to bounce back to normal. Overall, the current study provided additional information for PRRSV elimination in farrow-to-finish pig herds.

Keywords: PRRSV; elimination; farrow-to-finish.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Female
Porcine Reproductive and Respiratory Syndrome* / prevention & control
Porcine respiratory and reproductive syndrome virus* / genetics
Sus scrofa
Swine
Swine Diseases*
Weaning

Grants and funding

This work was supported by the Science and Technology Program of the Education Department of Jiangxi Province (grant number: GJJ190192), the Natural Science Foundation of Jiangxi Province (grant number: 20202BAB205004), the Natural Science Foundation of Jiangxi Province (grant number: 2020ACBL215007), The National Natural Science Foundation (grant number: 32260878), and the Program for Jiangxi Agriculture Research System (grant number: JXARS-01).