Other Novel PET Radiotracers for Breast Cancer

Sophia R O'Brien; Rebecca Ward; Grace G Wu; Sina Bagheri; Mahsa Kiani; Ashrit Challa; Gary A Ulaner; Austin R Pantel; Elizabeth S McDonald

doi:10.1016/j.cpet.2023.05.001

Other Novel PET Radiotracers for Breast Cancer

PET Clin. 2023 Oct;18(4):557-566. doi: 10.1016/j.cpet.2023.05.001. Epub 2023 Jun 25.

Authors

Sophia R O'Brien¹, Rebecca Ward², Grace G Wu², Sina Bagheri³, Mahsa Kiani², Ashrit Challa², Gary A Ulaner⁴, Austin R Pantel², Elizabeth S McDonald⁵

Affiliations

¹ Department of Radiology, Hospital of the University of Pennsylvania, 1 Donner, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: Sophia.Obrien@pennmedicine.upenn.edu.
² Department of Radiology, Hospital of the University of Pennsylvania, 1 Donner, 3400 Spruce Street, Philadelphia, PA 19104, USA.
³ Department of Radiology, Hospital of the University of Pennsylvania, 1 Donner, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: https://twitter.com/Sina_Bagherii.
⁴ Molecular Imaging and Therapy, Hoag Family Cancer Institute, Irvine, CA 92618, USA; Radiology and Translational Genomics, University of Southern California, Los Angeles, CA 90033, USA.
⁵ Department of Radiology, Hospital of the University of Pennsylvania, 1 Donner, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: elizabeth.mcdonald@pennmedicine.upenn.edu.

PMID: 37369615
DOI: 10.1016/j.cpet.2023.05.001

Abstract

Many novel PET radiotracers have demonstrated potential use in breast cancer. Although not currently approved for clinical use in the breast cancer population, these innovative imaging agents may one day play a role in the diagnosis, staging, management, and even treatment of breast cancer.

Keywords: Breast cancer; FAPI; FLT; FMISO; Fluciclovine; ImmunoPET; PARP; PET/CT.

Publication types

Review

MeSH terms

Breast Neoplasms* / diagnostic imaging
Female
Humans
Positron Emission Tomography Computed Tomography / methods
Positron-Emission Tomography / methods
Radiopharmaceuticals

Substances

Radiopharmaceuticals