A Highly Selective Schiff Base Based Chemodosimeter for the Detection of Perfluorooctanoic Acid by Optical Biosensor

J Fluoresc. 2024 Mar;34(2):787-794. doi: 10.1007/s10895-023-03298-w. Epub 2023 Jun 27.

Abstract

A simple imine derivative based sensor (IDP) has been synthesized and characterized by 1 H NMR, 13 C NMR and mass spectral techniques. IDP is more capable of detecting perfluorooctanoic acid (PFOA) in a selective and sensitive manner. The PFOA as a biomarker interacts with IDP and shows "TURN-ON" response by colorimetric and fluorimetric method. Under optimized experimental observations, the selective determination of PFOA using IDP among other competitors as biomolecules has been noticed. The detection limit is 0.31 × 10- 8 mol/L. The practical applications of the IDP is effectively evaluated in human biofluids and water samples.

Keywords: Competitive experiment; Fluorimetry biosensor; LOD; PFOA.

MeSH terms

  • Biosensing Techniques* / methods
  • Caprylates
  • Fluorocarbons*
  • Humans
  • Schiff Bases

Substances

  • perfluorooctanoic acid
  • Schiff Bases
  • Caprylates
  • Fluorocarbons