A systematic review on laparoscopic subtotal cholecystectomy for difficult gallbladders: a lifesaving bailout or an incomplete operation?

Ann R Coll Surg Engl. 2024 Mar;106(3):205-212. doi: 10.1308/rcsann.2023.0008. Epub 2023 Jun 27.

Abstract

Introduction: Laparoscopic subtotal cholecystectomy (LSTC) is a bailout procedure that is undertaken when it is not safe to proceed with a laparoscopic total cholecystectomy owing to dense adhesions in Calot's triangle. The main aim of this review was to investigate the early (≤30 days) and late (>30 days) morbidity and mortality of LSTC.

Methods: A literature search of the PubMed® (MEDLINE®), Google Scholar™ and Embase® databases was conducted to identify all studies on LSTC published between 1985 and December 2020. A systematic review was then performed.

Results: Overall, 45 studies involving 2,166 subtotal cholecystectomy patients (51% female) were identified for inclusion in the review. The mean patient age was 55 years (standard deviation: 15 years). Just over half (53%) of the patients had an elective procedure. The conversion rate was 6.2% (n=135). The most common indication was acute cholecystitis (49%). Different techniques were used, with the majority having a closed cystic duct/gallbladder stump (71%). The most common closure technique was intracorporeal suturing (53%), followed by endoloop closure (15%). Four patients (0.18%) died within thirty days of surgery. Morbidity within 30 days included bile duct injury (0.23%), bile leak (18%) and intra-abdominal collection (4%). Reoperation was reported in 23 patients (1.2%), most commonly for unresolving intra-abdominal collections and failed endoscopic retrograde cholangiopancreatography to control bile leak. Long-term follow-up was reported in 30 studies, the median follow-up duration being 22 months. Late morbidity included incisional hernias (6%), symptomatic gallstones (4%) and common bile duct stones (2%), with 2% of cases requiring completion of cholecystectomy.

Conclusions: LSTC is an acceptable alternative in patients with a "difficult" Calot's triangle.

Keywords: Biliary surgery; Gallbladder; Gallstones; Laparoscopic; Minimally invasive; Subtotal cholecystectomy.

Publication types

  • Systematic Review

MeSH terms

  • Cholecystectomy / adverse effects
  • Cholecystectomy / methods
  • Cholecystectomy, Laparoscopic* / adverse effects
  • Cholecystectomy, Laparoscopic* / methods
  • Cystic Duct
  • Gallstones* / surgery
  • Humans
  • Morbidity