A miniaturized hydrogen flame ionization detector based on integrated nozzle assembly and embedded sealing structure

Shenghong Li; Xuhui Geng; Kun Ding; Yan Gao; Yafeng Guan

doi:10.1016/j.talanta.2023.124806

A miniaturized hydrogen flame ionization detector based on integrated nozzle assembly and embedded sealing structure

Talanta. 2023 Dec 1:265:124806. doi: 10.1016/j.talanta.2023.124806. Epub 2023 Jun 17.

Authors

Shenghong Li¹, Xuhui Geng¹, Kun Ding¹, Yan Gao¹, Yafeng Guan²

Affiliations

¹ Department of Instrumentation & Analytical Chemistry, CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Key Laboratory of Deep-sea Composition Detection Technology of Liaoning Province, Dalian Institute of Chemical Physics, CAS, 457 Zhongshan Road, Dalian, 116023, China.
² Department of Instrumentation & Analytical Chemistry, CAS Key Laboratory of Separation Sciences for Analytical Chemistry, Key Laboratory of Deep-sea Composition Detection Technology of Liaoning Province, Dalian Institute of Chemical Physics, CAS, 457 Zhongshan Road, Dalian, 116023, China; Institute of Deep-Sea Science & Engineering, CAS, 28 Luhuitou Road, Sanya, 572000, China. Electronic address: guanyafeng@dicp.ac.cn.

PMID: 37364382
DOI: 10.1016/j.talanta.2023.124806

Abstract

A modified miniaturized hydrogen flame ionization detector (m-FID) was developed and evaluated. An integrated nozzle assembly was constructed to solve the gas leakage caused by adhesive crack during repeated high-low temperature processes or vibration. An embedded sealing structure was designed to realize the face sealing, thus improving the sealing stability and reliability of the m-FID. Polyimide was employed as seal and insulation material to ensure the detector can be used at 300 °C for a long term. The hydrogen and air consumption of the m-FID was 12 mL/min and 110 mL/min, which is about 1/3 of the FID gas consumption of commercial laboratory instruments. The limit of detection (LOD) for n-hexadecane was 3.2 × 10^-12 g/s, with a linear response range of nearly 5 orders of magnitude. Finally, it was installed onto an on-site gas chromatograph to detect drug samples with wide boiling point range from room temperature up to 535 °C.

Keywords: Hydrogen flame ionization detector; Miniaturization; Nozzle with embedded sealing structure; Polyimide; Reduced gases consumption.