ACUTE MACULAR NEURORETINOPATHY FOLLOWING SARS-CoV-2 VACCINATION

Retin Cases Brief Rep. 2023 Jul 1;17(4):438-440. doi: 10.1097/ICB.0000000000001222.

Abstract

Purpose: To report a case of acute macular neuroretinopathy (AMN) following SARS-CoV-2 vaccination.

Methods: Case report.

Results: An otherwise healthy 28-year-old white woman presented to an ophthalmology department with complaints of black paracentral vision scotomata on both eyes that appeared 2 days after receiving the first dose of Vaxzevria vaccine. Fundus examination revealed bilateral red brown petaloid lesions around the fovea. On spectral domain optical coherence tomography, a hyperreflective plaque between the outer plexiform and outer nuclear layers along with disruption of ellipsoid zone/interdigitation zone was observed. A diagnosis of AMN was made.

Conclusion: AMN may be an extremely rare adverse event of SARS-COV-2 vaccination, especially in patients with other risk factors.

Synopsis: An otherwise healthy 28-year-old white woman was diagnosed with AMN 2 days after SARS-CoV-2 vaccination.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • COVID-19 Vaccines / adverse effects
  • COVID-19* / prevention & control
  • Female
  • Humans
  • Macula Lutea* / pathology
  • Retinal Diseases* / diagnosis
  • Retinal Diseases* / etiology
  • Retinal Diseases* / pathology
  • SARS-CoV-2
  • Scotoma
  • Tomography, Optical Coherence / methods
  • Vaccination / adverse effects
  • White Dot Syndromes* / complications

Substances

  • COVID-19 Vaccines