Intracoronary imaging-guided rotational atherectomy combined with intravascular lithotripsy in the treatment of severe coronary artery calcification-A case report

Front Cardiovasc Med. 2023 Jun 9:10:1184237. doi: 10.3389/fcvm.2023.1184237. eCollection 2023.

Abstract

Background: Severe coronary artery calcification increases the difficulty of percutaneous coronary intervention procedures and impairs stent expansion. Herein, we report a case of a patient who was successfully treated with rotational atherectomy using a stepped burr strategy combined with intravascular lithotripsy for plaque modification under intracoronary imaging.

Case summary: A 65 year-old woman presented to our hospital with recurrent chest pain evolving for 1 year. Coronary angiography showed approximately 80% stenosis of the proximal mid-left anterior descending artery. Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) revealed a 360° annular calcification. The calcification was rotablated with 1.5 and 1.75 burrs, and the lesion was undilatable with a 3.0 mm non-compliant balloon at 14 atm. Subsequently, the intravascular lithotripsy was reset for the modification of the calcified lesion. A shockwave balloon measuring 3.0 mm × 12 mm was delivered, and 40 pulses were performed at 6 atm. Intravascular imaging modalities (IVUS and OCT) revealed a circumferential calcified plaque with deep fractures. After post-balloon expansion followed by drug-eluting stent placement with a final stent expansion of 84%, there were no intraoperative complications and no major adverse cardiovascular events within 90 days postoperatively.

Conclusion: A combination of rotational atherectomy and intravascular lithotripsy may be an effective and complementary strategy for the treatment of severely calcified lesions that cannot be resolved using a single procedure. However, more clinical studies are required to clarify this finding.

Keywords: intracoronary imaging; intravascular lithotripsy; percutaneous coronary intervention; rotational atherectomy; severe coronary artery calcification.

Publication types

  • Case Reports

Grants and funding

This study was supported in part by application of optical coherence tomography(OCT) in vivo evaluation of drug balloon in coronary artery lesions, Finance Department of Jilin Province (2019SCZ057) and exploration of the mechanism of increased risk of hypertension at the rs11169571 polymorphic locus of ATF1 gene, Health Department of Jilin Province(2015Z012).