Recent progress on rapid diagnosis of COVID-19 by point-of-care testing platforms

Ya-Nan Tang; Dingding Jiang; Xuejun Wang; Yunqi Liu; Dacheng Wei

doi:10.1016/j.cclet.2023.108688

Recent progress on rapid diagnosis of COVID-19 by point-of-care testing platforms

Chin Chem Lett. 2023 Jun 15:108688. doi: 10.1016/j.cclet.2023.108688. Online ahead of print.

Authors

Ya-Nan Tang^{1

2}, Dingding Jiang^{1

2}, Xuejun Wang^{1

2}, Yunqi Liu², Dacheng Wei^{1

2}

Affiliations

¹ State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China.
² Institute of Molecular Materials and Devices, Fudan University, Shanghai 200433, China.

Abstract

The outbreak of COVID-19 has drawn great attention around the world. SARS-CoV-2 is a highly infectious virus with occult transmission by many mutations and a long incubation period. In particular, the emergence of asymptomatic infections has made the epidemic even more severe. Therefore, early diagnosis and timely management of suspected cases are essential measures to control the spread of the virus. Developing simple, portable, and accurate diagnostic techniques for SARS-CoV-2 is the key to epidemic prevention. The advantages of point-of-care testing technology make it play an increasingly important role in viral detection and screening. This review summarizes the point-of-care testing platforms developed by nucleic acid detection, immunological detection, and nanomaterial-based biosensors detection. Furthermore, this paper provides a prospect for designing future highly accurate, cheap, and convenient SARS-CoV-2 diagnostic technology.

Keywords: Asymptomatic infection; Biosensors; COVID-19; Nucleic acid detection; Point-of-care testing platforms.

Publication types

Review