Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review

Rajib Chandra Das; Zubair Ahmed Ratan; Md Mustafizur Rahman; Nusrat Jahan Runa; Susmita Mondal; Konstantin Konstantinov; Hassan Hosseinzadeh; Jae Youl Cho

doi:10.1016/j.jgr.2023.03.002

Antiviral activities of ginseng and its potential and putative benefits against monkeypox virus: A mini review

J Ginseng Res. 2023 Apr 1;47(6):687-693. doi: 10.1016/j.jgr.2023.03.002. Online ahead of print.

Authors

Rajib Chandra Das^{1

2}, Zubair Ahmed Ratan^{3

4}, Md Mustafizur Rahman⁵, Nusrat Jahan Runa⁶, Susmita Mondal¹, Konstantin Konstantinov¹, Hassan Hosseinzadeh⁴, Jae Youl Cho^{7

8

9}

Affiliations

¹ Institute for Superconducting and Electronics Materials (ISEM), University of Wollongong (UOW), Wollongong, NSW, 2522, Australia.
² Department of Applied Chemistry and Chemical Engineering, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh.
³ Department of Biomedical Engineering, Khulna University of Engineering & Technology, Khulna, 9203, Bangladesh.
⁴ School of Health and Society, University of Wollongong, NSW, 2500, Australia.
⁵ Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b).
⁶ Sylhet MAG Osmani Medical College, Sylhet, Bangladesh.
⁷ Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, Republic of Korea.
⁸ Department of Biocosmetics, Sungkyunkwan University, Suwon, Republic of Korea.
⁹ Research Institute of Biomolecule Control and Biomedical Institute for Convergence at SKKU, Suwon, Republic of Korea.

Abstract

Due to the Covid-19 pandemic more than 6 million people have died, and it has bought unprecedented challenges to our lives. The recent outbreak of monkeypox virus (MPXV) has brought out new tensions among the scientific community. Currently, there is no specific treatment protocol for MPXV. Several antivirals, vaccinia immune globulin (VIG) and smallpox vaccines have been used to treat MPXV. Ginseng, one of the more famous among traditional medicines, has been used for infectious disease for thousands of years. It has shown promising antiviral effects. Ginseng could be used as a potential adaptogenic agent to help prevent infection by MPXV along with other drugs and vaccines. In this mini review, we explore the possible use of ginseng in MPXV prevention based on its antiviral activity.

Keywords: Korean ginseng; Panax ginseng; monkeypox virus; viral diseases.

Publication types

Review