Exploring plant polyphenols as anti-allergic functional products to manage the growing incidence of food allergy

Tianxiang Wu; Zhenxing Li; Yanyan Wu; Xianqing Yang; Laihao Li; Shengjun Chen; Bo Qi; Yueqi Wang; Chunsheng Li; Yongqiang Zhao

doi:10.3389/fnut.2023.1102225

Exploring plant polyphenols as anti-allergic functional products to manage the growing incidence of food allergy

Front Nutr. 2023 Jun 9:10:1102225. doi: 10.3389/fnut.2023.1102225. eCollection 2023.

Authors

Tianxiang Wu^{1

2

3}, Zhenxing Li^{2

4}, Yanyan Wu^{1

3

4}, Xianqing Yang^{1

3

4}, Laihao Li^{1

3

4}, Shengjun Chen^{1

3}, Bo Qi^{1

3}, Yueqi Wang^{1

3}, Chunsheng Li^{1

4}, Yongqiang Zhao^{1

3

4}

Affiliations

¹ Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs, National R&D Center for Aquatic Product Processing, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, China.
² Food Safety Laboratory, Ocean University of China, Qingdao, China.
³ Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang, China.
⁴ Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian, China.

Abstract

The active substances derived from plants have received increasing attention owing to their wide range of pharmacological applications, including anti-tumor, anti-allergic, anti-viral, and anti-oxidative activities. The allergy epidemic is a growing global public health problem that threatens human health and safety. Polyphenols from plants have significant anti-allergic effects and are an important source of anti-allergic drug research and development. Here, we describe recent advances in the anti-allergic efficacy of plant polyphenols, including their comprehensive effects on cellular or animal models. The current issues and directions for future development in this field are discussed to provide a theoretical basis for the development and utilization of these active substances as anti-allergic products.

Keywords: active substances; allergen; anti-allergic; immune activity; mechanism; plant polyphenols.

Publication types

Review

Grants and funding

We are grateful for the financial support from the National Key R&D Program of China (2018YFD0901006), China Agriculture Research System of MOF and MARA (CARS-50), and Central Public-interest Scientific Institution Basal Research Fund, CAFS (2020TD73).