AlphaFold and the future of structural biology

Acta Crystallogr F Struct Biol Commun. 2023 Jul 1;79(Pt 7):166-168. doi: 10.1107/S2053230X23004934. Epub 2023 Jun 26.

Abstract

This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.

Keywords: AlphaFold; cryo-EM; crystallography; protein structure prediction.

MeSH terms

  • Biology*
  • Cryoelectron Microscopy
  • Crystallography, X-Ray
  • Protein Conformation