Patients with intrahepatic cholangiocarcinoma have a poor overall prognosis and a low long-term survival rate. Currently, multimodal treatment is the mainstay of treatment, and surgical resection is the most important treatment for patients with intrahepatic cholangiocarcinoma for a long-term survival. Although the treatment strategies have been constantly updated in recent years to improve survival rates, there are still many controversial issues in the existing treatment strategies. Based on our center's clinical practice and recent research progress, analyzes several issues affecting long-term survival were analyzed based on three aspects: accurate clinical assessment methods, the related decisions making for surgical resection, and the strategies of precision medicine.
肝内胆管癌患者总体预后差，长期生存比例低。目前治疗以多模式治疗为主，手术切除是肝内胆管癌患者获得长期生存的最重要手段。尽管近年来治疗手段不断更新，以期提高生存效果，但现有治疗策略仍存较多争议性问题，笔者结合本中心的临床实践及近年来的研究进展，从肝内胆管癌患者的临床评估手段、外科切除的相关决策及精准治疗方案等三方面，分析影响长期生存的若干问题，对现有治疗模式进行再思考。.