Nonnegligible Seroprevalence and Predictors of Murine Typhus, Japan

Emerg Infect Dis. 2023 Jul;29(7):1438-1442. doi: 10.3201/eid2907.230037.

Abstract

To elucidate the epidemiology of murine typhus, which is infrequently reported in Japan, we conducted a cross-sectional study involving 2,382 residents of rickettsiosis-endemic areas in Honshu Island during August-November 2020. Rickettsia typhi seroprevalence rate was higher than that of Orientia tsutsugamushi, indicating that murine typhus is a neglected disease.

Keywords: Japan; Japanese spotted fever; Orientia tsutsugamushi; Rickettsia japonica; Rickettsia typhi; bacteria; cross-sectional studies; flea borne; murine typhus; rickettsia; scrub typhus; seroepidemiological studies; spotted fever group rickettsiosis; typhus; vector-borne infections.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cross-Sectional Studies
  • Humans
  • Japan / epidemiology
  • Mice
  • Orientia tsutsugamushi*
  • Rickettsia typhi
  • Scrub Typhus* / epidemiology
  • Scrub Typhus* / microbiology
  • Seroepidemiologic Studies
  • Typhus, Endemic Flea-Borne* / epidemiology