Infective endocarditis is associated with acute heart failure if the valve involvement leads to significant alteration in the hemodynamics. Vegetation in infective endocarditis invades the tissue causing disruption of the anatomical integrity of the valve structure. Heart failure in infective endocarditis is associated with high morbidity and mortality despite advances in surgical and medical therapies. Aortic valve vegetation may cause involvement of mitral valve through different mechanisms. Here, we present a case of infective endocarditis with vegetation on the aortic valve causing perforation of anterior mitral leaflet leading to severe mitral regurgitation.
Supplementary information: The online version contains supplementary material available at 10.1007/s12055-023-01486-8.
Keywords: Infective endocarditis; Mitral leaflet perforation; Regurgitation.
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