The impact of COVID-19 infection on cytochrome P450 3A4-mediated drug metabolism and drug interactions

Expert Opin Drug Metab Toxicol. 2023 Jan-Jun;19(6):329-332. doi: 10.1080/17425255.2023.2228680. Epub 2023 Jun 26.

Authors

Samuel Villemure¹, Shanna C Trenaman^{1

2}, Kerry B Goralski^{1

3

4

5}

Affiliations

¹ College of Pharmacy, Dalhousie University, Halifax, Nova Scotia, Canada.
² Nova Scotia Health Authority, Halifax, Nova Scotia.
³ Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
⁴ Department of Pediatrics, IWK Health Centre.
⁵ Beatrice Hunter Cancer Research Institute, Halifax, Nova Scotia, Canada.

PMID: 37345482
DOI: 10.1080/17425255.2023.2228680

No abstract available

Keywords: Cytochrome P450 (CYP); SARs-CoV-2; infection; inflammation; liver; therapeutics.

Publication types

Editorial

MeSH terms

COVID-19* / metabolism
Cytochrome P-450 CYP3A / metabolism
Drug Interactions
Humans
Microsomes, Liver / metabolism

Substances

Cytochrome P-450 CYP3A