Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability

Oncotarget. 2023 Jun 21:14:653-655. doi: 10.18632/oncotarget.28440.
No abstract available

Keywords: AMG-176; AZD5991; B-cell leukemia; MCL-1 inhibitor; MCL-1 protein.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Antineoplastic Agents* / pharmacology
  • Apoptosis
  • Cell Line, Tumor
  • Humans
  • Myeloid Cell Leukemia Sequence 1 Protein / metabolism
  • Protein Stability
  • Proto-Oncogene Proteins c-bcl-2 / metabolism

Substances

  • Myeloid Cell Leukemia Sequence 1 Protein
  • Antineoplastic Agents
  • Proto-Oncogene Proteins c-bcl-2