A glimpse into Long COVID characteristics and the mental health impact within a highly vaccinated population: a Malta observational study

Ann Ist Super Sanita. 2023 Apr-Jun;59(2):101-107. doi: 10.4415/ANN_23_02_02.

Abstract

Background: Post-acute COVID-19 consequences are gaining global recognition. This study explores Long COVID characteristics and associated mental health impact/s among the highly vaccinated adult population of Malta.

Methods: A social media survey gathered demographics, vaccination, and COVID-19 data. Generalised Anxiety Disorder and Patient Health Questionnaire-9 assessment tools were used for anxiety and depression. Quantitative analyses were performed.

Results: 41% reported Long COVID, mostly female, 30-39 years, absence of chronic disease/s and vaccinated. Shortness of breath commonest persistent symptom among males, and fatigue for females. Significantly higher depression scores were present in Long COVID cohort compared to no persistent symptoms (p=0.001) and never acquiring COVID-19 (p=<0.01). A significant higher anxiety scores was present for Long COVID cohort than never acquiring COVID-19 (p=<0.01).

Conclusions: Long COVID occurs even in healthy individuals and vaccinated, while exacerbating mental health burdens. Urgent action is required to manage Long COVID and preventing the sequela.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Anxiety / epidemiology
  • COVID-19* / epidemiology
  • Depression / epidemiology
  • Female
  • Humans
  • Male
  • Malta / epidemiology
  • Mental Health
  • Post-Acute COVID-19 Syndrome