The Current Limitations and Advanced Analysis of Hemodynamic Study of Cerebral Aneurysms

Neurointervention. 2023 Jun;18(2):107-113. doi: 10.5469/neuroint.2023.00164. Epub 2023 Jun 20.

Abstract

Among the various perspectives on cerebrovascular diseases, hemodynamic analysis-which has recently garnered interest-is of great help in understanding cerebrovascular diseases. Computational fluid dynamics (CFD) analysis has been the primary hemodynamic analysis method, and studies on cerebral aneurysms have been actively conducted. However, owing to the intrinsic limitations of the analysis method, the role of wall shear stress (WSS), the most representative parameter, remains controversial. High WSS affects the formation of cerebral aneurysms; however, no consensus has been reached on the role of WSS in the growth and rupture of cerebral aneurysms. Therefore, this review aimed to briefly introduce the up-to-date results and limitations made through CFD analysis and to inform the need for a new hemodynamic analysis method.

Keywords: Cerebral aneurysm; Computational fluid dynamics; Fluid-structure interaction; Hemodynamics; Wall shear stress.

Publication types

  • Review