Numerical simulation of flow-diverting stent: comparison between branches in bifurcation brain aneurysm

Biomech Model Mechanobiol. 2023 Dec;22(6):1801-1814. doi: 10.1007/s10237-023-01733-2. Epub 2023 Jun 19.

Abstract

The usage of flow-diverting stents in the treatment of intracranial aneurysms is widespread due to their high success and low complication rates. However, their use is still not officially recommended for bifurcation aneurysms, as there is a risk of generating ischemic complications due to the reduced blood flow to the jailed branch. Many works utilize computational fluid dynamics (CFD) to study how hemodynamic variables respond to flow diverter placement, but few seem to use it to verify flow variation between branches of bifurcation aneurysms and to aid in the choice of the best ramification for device placement. This investigation was performed in the present work, by comparing wall shear stress (WSS) and flowrates for a patient-specific scenario of a middle cerebral artery (MCA) aneurysm, considering device placement on each branch. A secondary objective was to follow a methodology that provides fast results, envisioning application to daily medical practice. The device was simplified as a homogeneous porous medium, and extreme porosity values were simulated for comparison. Results suggest that stent placement on either branch is both safe and effective, significantly reducing WSS and flow into the aneurysm while maintaining flow to the different ramifications within acceptable thresholds.

Keywords: Boundary condition; Computational fluid dynamics; Flow-diverting stent; Flowrate distribution; Middle cerebral artery; Porous medium.

MeSH terms

  • Computer Simulation
  • Hemodynamics
  • Humans
  • Hydrodynamics
  • Intracranial Aneurysm* / surgery
  • Stents