Objective: To review the research progress of the feasibility of a new treatment method for atrophic rhinitis (ATR) based on tissue engineering technology (seed cells, scaffold materials, and growth factors), and provide new ideas for the treatment of ATR.
Methods: The literature related to ATR was extensively reviewed. Focusing on the three aspects of seed cells, scaffold materials, and growth factors, the recent research progress of ATR treatment was reviewed, and the future directions of tissue engineering technology to treat ATR were proposed.
Results: The pathogenesis and etiology of ATR are still unclear, and the effectiveness of the current treatments are still unsatisfactory. The construction of a cell-scaffold complex with sustained and controlled release of exogenous cytokines is expected to reverse the pathological changes of ATR, promoting the regeneration of normal nasal mucosa and reconstructing the atrophic turbinate. In recent years, the research progress of exosomes, three-dimensional printing, and organoids will promote the development of tissue engineering technology for ATR.
Conclusion: Tissue engineering technology can provide a new treatment method for ATR.
目的: 综述组织工程技术（种子细胞、支架材料联合生长因子）治疗萎缩性鼻炎（atrophic rhinitis，ATR）可行性的相关研究进展，为ATR的治疗提供新思路。.
方法: 广泛查阅近年国内外ATR相关文献，围绕种子细胞、支架材料以及生长因子三要素，对组织工程技术治疗ATR 可行性的相关研究进展进行综述，并提出组织工程技术治疗ATR的未来趋势与方向。.
结果: ATR的发病机制及病因尚不明确，目前各治疗方案疗效尚无法达到满意水平。构建细胞-支架复合体缓释外源性细胞因子体系有望逆转ATR病理变化，促进正常鼻黏膜再生，重构萎缩的鼻甲。近年来，外泌体、3D打印、类器官的研究将推动组织工程技术在ATR治疗中的应用与发展。.
结论: 组织工程技术将为解决ATR治疗难题提供新的方案。.
Keywords: Atrophic rhinitis; repair and reconstruction; tissue engineering technology.