Transapical Transcatheter Mitral Valve Implantation with the Tendyne Valve: The Swiss Experience

Maria Nucera; Jules Miazza; Fabien Praz; Christoph Kaiser; Matthias Siepe; David Reineke; Oliver Reuthebuch

doi:10.1055/s-0043-1769099

Transapical Transcatheter Mitral Valve Implantation with the Tendyne Valve: The Swiss Experience

Thorac Cardiovasc Surg. 2023 Jun 16. doi: 10.1055/s-0043-1769099. Online ahead of print.

Authors

Maria Nucera¹, Jules Miazza², Fabien Praz³, Christoph Kaiser⁴, Matthias Siepe¹, David Reineke¹, Oliver Reuthebuch²

Affiliations

¹ Department of Cardiac Surgery, Cardiovascular Center, Inselspital University Hospital Bern, Bern, Switzerland.
² Department of Cardiac Surgery, Universitätsspital Basel, Basel, BS, Switzerland.
³ Department of Cardiology, Inselspital University Hospital Bern, Bern, Switzerland.
⁴ Department of Cardiology, Universitätsspital Basel, Basel, BS, Switzerland.

PMID: 37327913
DOI: 10.1055/s-0043-1769099

Abstract

Background: The aim of this study was to report outcomes of all patients undergoing transcatheter mitral valve implantation with the Tendyne Mitral Valve System (Tendyne) in Switzerland.

Methods: We retrospectively analyzed preoperative echocardiographic and computed tomography (CT) data, procedural findings, and 30-day and 1-year follow-up echocardiographic and clinical data of patients who underwent transcatheter mitral valve implantation with Tendyne in Switzerland.

Results: A total of 24 patients (age, 74.8 ± 7.8 years; 67% male) underwent transapical transcatheter mitral valve implantation with Tendyne between June 2020 and October 2022. Technical success rate was 96%. In five patients, concomitant interventions in the form of transcatheter aortic valve implantation (one patient), minimally invasive direct coronary artery bypass (one patient), and transcatheter edge-to-edge repair (three patients) were performed prior to or after the index procedure. There was one device embolization, and two patients required valve retrieval. In-hospital outcomes included one stroke and three major bleeding events. None of the patients died within 30 days. Two patients were rehospitalized for decompensated heart failure. At 1-year follow-up, there were three noncardiovascular-related deaths.

Conclusion: Transcatheter mitral valve implantation with Tendyne is feasible to treat polymorbid patients suffering from complex mitral valve disease as well as patients with previous mitral interventions. Perioperative risk was acceptable and procedural success high.