Sinogram Interpolation Inspired by Single-Image Super Resolution

J Biotechnol Appl. 2023;2(1):1010. Epub 2023 May 15.

Abstract

Computed tomography is a medical imaging procedure used to estimate the interior of a patient or an object. Radiation scans are taken at regularly spaced angles around the object, forming a sinogram. This sinogram is then reconstructed into an image representing the contents of the object. This results in a fair amount of radiation exposure for the patient, which increases the risk of cancer. Less radiation and fewer views, however, leads to inferior image reconstruction. To solve this sparse-view problem, a deep-learning model is created that takes as input a sparse sinogram and outputs a sinogram with interpolated data for additional views. The architecture of this model is based on the super-resolution convolutional neural network. The reconstruction of model-interpolated sinograms has less mean-squared error than the reconstruction of the sparse sinogram. It also has less mean-squared error than a reconstruction of a sinogram interpolated using the popular bilinear image-resizing algorithm. This model can be easily adapted to different image sizes, and its simplicity translates into efficiency in both time and memory requirements.

Keywords: Deep learning; Limited data imaging; Machine learning; Medical imaging; Tomography.