Challenges in Accurate Diagnosis of HCC in FALD: A Case Series

Pediatr Cardiol. 2023 Oct;44(7):1447-1453. doi: 10.1007/s00246-023-03207-9. Epub 2023 Jun 15.

Abstract

Patients with single ventricle cardiac disease palliated with Fontan procedures inevitably develop Fontan-Associated Liver Disease (FALD), which poses a significant risk for hepatocellular carcinoma (HCC). Standard imaging criteria for the diagnosis of cirrhosis are not reliable due to parenchymal heterogeneity of FALD. We present 6 cases to demonstrate our center's experience and the challenges in diagnosing HCC within this patient population.

Keywords: Fontan; Fontan associated liver disease; Hepatocellular carcinoma; Single ventricle.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular* / diagnostic imaging
  • Fontan Procedure*
  • Humans
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / diagnostic imaging
  • Liver Neoplasms* / diagnostic imaging
  • Postoperative Complications / epidemiology
  • Univentricular Heart*