Discovery of three novel HLA-DPA1 alleles, HLA-DPA1*01:147N, 01:03:47, and 02:106 using next-generation sequencing

HLA. 2023 Sep;102(3):385-387. doi: 10.1111/tan.15125. Epub 2023 Jun 14.

Authors

Qian Hu^{1

2}, Caitlyn Burns¹, Danielle Christian¹, Guang Yang¹, Noureddine Berka^{1

2}

Affiliations

¹ Histocompatibility and Immunogenetics Laboratory, Alberta Precision Laboratories, Calgary, Canada.
² Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada.

PMID: 37315941
DOI: 10.1111/tan.15125

Abstract

Characterization of three novel HLA-DPA1 alleles bearing null, synonymous, and non-synonymous mutations.

Keywords: HLA-DPA1; next-generation sequencing; novel allele.

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
HLA-DP alpha-Chains* / genetics
High-Throughput Nucleotide Sequencing*
Humans

Substances

HLA-DPA1 antigen
HLA-DP alpha-Chains