1 Intensive Care Medicine, Adult Critical Care Unit, Royal London Hospital, Barts Health NHS Trust, London, UK. b.fazzini@qmul.ac.uk.
2 Barts and The London School of Medicine & Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK. b.fazzini@qmul.ac.uk.
3 Adult Critical Care Unit, Royal London Hospital, Whitechapel, London, UK. b.fazzini@qmul.ac.uk.
4 Intensive Care Medicine, Adult Critical Care Unit, Royal London Hospital, Barts Health NHS Trust, London, UK.
5 Barts and The London School of Medicine & Dentistry, William Harvey Research Institute, Queen Mary University of London, London, UK.
6 Anesthesia and Intensive Care Medicine, St Bartholomew Hospital, Barts Health NHS Trust, London, UK.