Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis

Am J Gastroenterol. 2023 Nov 1;118(11):2088-2092. doi: 10.14309/ajg.0000000000002362. Epub 2023 Jun 14.

Abstract

Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis.

Methods: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients.

Results: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission.

Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.

Publication types

  • Multicenter Study

MeSH terms

  • Colitis* / complications
  • Colitis* / diagnosis
  • Colitis* / epidemiology
  • Diverticulum* / complications
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Treatment Outcome